Bramble

Bramble is a specialized runeword in Diablo 2 Resurrected designed for poison-focused builds. Created with Ral + Ohm + Sur + Eth in 4-socket body armor, this runeword offers unmatched poison damage amplification that surpasses even endgame alternatives.

Poison Damage Supremacy

The defining feature of Bramble is its +25-50% to Poison Skill Damage modifier—the only runeword in the game with this property. For Poison Nova Necromancers, Rabies Druids, and Plague Javazons, this bonus far exceeds the +2 to All Skills offered by versatile alternatives like Enigma or Chains of Honor. Combined with +100% Poison Resist and Increase Maximum Mana 5%, it creates a perfectly synergized armor for poison specialists.

Best Uses & Builds

Bramble is best-in-slot armor for builds where poison is the primary damage source. Poison Nova Necromancers benefit most, as their damage output scales dramatically with the poison skill damage bonus. Rabies Druids gain substantial damage increases for their melee-range poison attacks, while Plague Javazons using Plague runeword weapons see significant boosts to their poison cloud damage.

The Level 15-21 Thorns Aura When Equipped adds a unique defensive layer, particularly valuable for Necromancers whose minions inherit the aura, turning summoned armies into retaliatory damage dealers. The +50% Faster Hit Recovery and +13 Life After Each Kill provide essential survivability.

Best Bases

Archon Plate is the premier choice, offering high defense with manageable strength requirements (103 strength). Light armor bases like Dusk Shroud or Wyrmhide work for lower strength builds. The +300 Defense bonus ensures solid protection regardless of base choice, though superior bases with enhanced defense provide optimal results.